Biophysical Characterization of α-Synuclein and Rotenone Interaction

Biophysical Characterization of α-Synuclein and Rotenone Interaction

Previous studies revealed that pesticides interact with α-synuclein and accelerate the rate of fibrillation. These results are consistent with the prevailing hypothesis that the direct interaction of α-synuclein with pesticides is one of many suspected factors leading to α-synuclein fibrillation and...

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Bibliographic Details
Main Authors: Anthony L. Fink, Ólöf Einarsdóttir, Blanca A. Silva, Vladimir N. Uversky
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Biomolecules
Subjects:
α-Synuclein
Parkinson’s disease
environmental toxin
misfolding
fibrillation
intrinsically disordered protein
pesticide
agrochemical
rotenone
Online Access:http://www.mdpi.com/2218-273X/3/3/703

Internet

http://www.mdpi.com/2218-273X/3/3/703

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