Abortive autophagy induces endoplasmic reticulum stress and cell death in cancer cells.

Abortive autophagy induces endoplasmic reticulum stress and cell death in cancer cells.

Autophagic cell death or abortive autophagy has been proposed to eliminate damaged as well as cancer cells, but there remains a critical gap in our knowledge in how this process is regulated. The goal of this study was to identify modulators of the autophagic cell death pathway and elucidate their e...

Full description

Bibliographic Details
Main Authors: Sofie Claerhout, Bhaskar Dutta, Wouter Bossuyt, Fan Zhang, Catherine Nguyen-Charles, Jennifer B Dennison, Qinghua Yu, Shuangxing Yu, Gábor Balázsi, Yiling Lu, Gordon B Mills
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3383753?pdf=render

Internet

http://europepmc.org/articles/PMC3383753?pdf=render

Similar Items