A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T–Hg2+–T mismatched DNA

We report herein the use of an exonuclease III and G-quadruplex probe to construct a G-quadruplex-based luminescence detection platform for Hg2+. Unlike common DNA-based Hg2+ detection methods, when using the dsDNA probe to monitor the hairpin formation, the intercalation of the dsDNA probe may be i...

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Bibliographic Details
Main Authors: Wanhe Wang, Tian-Shu Kang, Philip Wai Hong Chan, Jin-Jian Lu, Xiu-Ping Chen, Chung-Hang Leung, Dik-Lung Ma
Format: Article
Language:English
Published: Taylor & Francis Group 2015-12-01
Series:Science and Technology of Advanced Materials
Subjects:
Online Access:http://dx.doi.org/10.1088/1468-6996/16/6/065004