The CNOT4 Subunit of the CCR4‐NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis

Abstract The CCR4‐NOT complex is a major mRNA deadenylase in eukaryotes, comprising the catalytic subunits CNOT6/6L and CNOT7/8, as well as CNOT4, a regulatory subunit with previously undetermined functions. These subunits have been hypothesized to play synergistic biochemical functions during devel...

Full description

Bibliographic Details
Main Authors: Xing‐Xing Dai, Yu Jiang, Jia‐Hui Gu, Zhi‐Yan Jiang, Yun‐Wen Wu, Chao Yu, Hao Yin, Jue Zhang, Qing‐Hua Shi, Li Shen, Qian‐Qian Sha, Heng‐Yu Fan
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202003636