The “Connection” Between HIV Drug Resistance and RNase H

Currently, nucleoside reverse transcriptase inhibitors (NRTIs) and nonnucleoside reverse transcriptase inhibitors (NNRTIs) are two classes of antiretroviral agents that are approved for treatment of HIV-1 infection. Since both NRTIs and NNRTIs target the polymerase (pol) domain of reverse transcript...

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Bibliographic Details
Main Authors: Krista A. Delviks-Frankenberry, Vinay K. Pathak, Galina N. Nikolenko
Format: Article
Language:English
Published: MDPI AG 2010-07-01
Series:Viruses
Subjects:
HIV
Online Access:http://www.mdpi.com/1999-4915/2/7/1476/