A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology.

A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology.

CD8 T cells are involved in pathogen clearance and infection-induced pathology in respiratory syncytial virus (RSV) infection. Studying bulk responses masks the contribution of individual CD8 T cell subsets to protective immunity and immunopathology. In particular, the roles of subdominant responses...

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Bibliographic Details
Main Authors: Jie Liu, Elias K Haddad, Joshua Marceau, Kaitlyn M Morabito, Srinivas S Rao, Ali Filali-Mouhim, Rafick-Pierre Sekaly, Barney S Graham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4778879?pdf=render

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http://europepmc.org/articles/PMC4778879?pdf=render

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