Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.

Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.

The human retinal pigment epithelium (RPE) plays an important role in the pathogenesis of age related macular degeneration (AMD). AMD is the leading cause of blindness worldwide. There is currently no effective treatment available. Preclinical studies in AMD mouse models are essential to develop new...

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Bibliographic Details
Main Authors: Anna Bennis, Theo G M F Gorgels, Jacoline B Ten Brink, Peter J van der Spek, Koen Bossers, Vivi M Heine, Arthur A Bergen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4627757?pdf=render

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http://europepmc.org/articles/PMC4627757?pdf=render

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