MicroRNA-3613-5p Promotes Lung Adenocarcinoma Cell Proliferation through a RELA and AKT/MAPK Positive Feedback Loop

MicroRNA-3613-5p Promotes Lung Adenocarcinoma Cell Proliferation through a RELA and AKT/MAPK Positive Feedback Loop

Aberrant activation of nuclear factor κB (NF-κB)/RELA is often found in lung adenocarcinoma (LUAD). In this study, we determined that microRNA-3613-5p (miR-3613-5p) plays a crucial role in RELA-mediated post-transcriptional regulation of LUAD cell proliferation. Expression of miR-3613-5p in clinical...

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Bibliographic Details
Main Authors: Tao He, Hongyou Shen, Shuangmiao Wang, Yanfang Wang, Zhiwei He, Litong Zhu, Xinyue Du, Dan Wang, Jiao Li, Shizhen Zhong, Wenhua Huang, Huiling Yang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312030295X

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http://www.sciencedirect.com/science/article/pii/S216225312030295X

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