TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1

TIM-3 drives temporal differences in restimulation-induced cell death sensitivity in effector CD8+ T cells in conjunction with CEACAM1

Abstract Immune homeostasis depends upon effective clearance of pathogens while simultaneously preventing autoimmunity and immunopathology in the host. Restimulation-induced cell death (RICD) is one such mechanism where by activated T cells receive subsequent antigenic stimulation, reach a critical...

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Bibliographic Details
Main Authors: Camille M. Lake, Kelsey Voss, Bradly M. Bauman, Katherine Pohida, Timothy Jiang, Gabriela Dveksler, Andrew L. Snow
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03689-6

Internet

https://doi.org/10.1038/s41419-021-03689-6

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