Modeling chemotaxis reveals the role of reversed phosphotransfer and a bi-functional kinase-phosphatase.

Understanding how multiple signals are integrated in living cells to produce a balanced response is a major challenge in biology. Two-component signal transduction pathways, such as bacterial chemotaxis, comprise histidine protein kinases (HPKs) and response regulators (RRs). These are used to sense...

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Bibliographic Details
Main Authors: Marcus J Tindall, Steven L Porter, Philip K Maini, Judith P Armitage
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2924250?pdf=render