House dust mite sensitization drives cross-reactive immune responses to homologous helminth proteins.

The establishment of type 2 responses driven by allergic sensitization prior to exposure to helminth parasites has demonstrated how tissue-specific responses can protect against migrating larval stages, but, as a consequence, allow for immune-mediated, parasite/allergy-associated morbidity. In this...

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Bibliographic Details
Main Authors: Pedro Henrique Gazzinelli-Guimaraes, Sasisekhar Bennuru, Rafael de Queiroz Prado, Alessandra Ricciardi, Joshua Sciurba, Jonah Kupritz, Matthew Moser, Olena Kamenyeva, Thomas B Nutman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009337