Metabolic engineering strategies for optimizing acetate reduction, ethanol yield and osmotolerance in Saccharomyces cerevisiae

Metabolic engineering strategies for optimizing acetate reduction, ethanol yield and osmotolerance in Saccharomyces cerevisiae

Abstract Background Glycerol, whose formation contributes to cellular redox balancing and osmoregulation in Saccharomyces cerevisiae, is an important by-product of yeast-based bioethanol production. Replacing the glycerol pathway by an engineered pathway for NAD+-dependent acetate reduction has been...

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Bibliographic Details
Main Authors: Ioannis Papapetridis, Marlous van Dijk, Antonius J. A. van Maris, Jack T. Pronk
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Biotechnology for Biofuels
Subjects:
Yeast
NADH
NADPH
Redox engineering
Acetic acid
Osmotic stress
Online Access:http://link.springer.com/article/10.1186/s13068-017-0791-3

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http://link.springer.com/article/10.1186/s13068-017-0791-3

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