The rates of protein synthesis and degradation account for the differential response of neurons to spaced and massed training protocols.

The sensory-motor neuron synapse of Aplysia is an excellent model system for investigating the biochemical changes underlying memory formation. In this system, training that is separated by rest periods (spaced training) leads to persistent changes in synaptic strength that depend on biochemical pat...

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Bibliographic Details
Main Authors: Faisal Naqib, Carole A Farah, Christopher C Pack, Wayne S Sossin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3248386?pdf=render