Follow-up on genome-wide main effects: Do polymorphisms modify the air pollution effect on lung function decline in adults?

Improved air quality has been found associated with attenuated age-related decline in lung function. But whether genetic polymorphisms strongly associated with lung function play a modifying role in this attenuation process has so far not been investigated.We selected ten single nucleotide polymorph...

Full description

Bibliographic Details
Main Authors: Gian Andri Thun, Medea Imboden, Nino Künzli, Thierry Rochat, Dirk Keidel, Margot Haun, Christian Schindler, Florian Kronenberg, Nicole M. Probst-Hensch
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412013003012