Regulation of CEACAM Family Members by IBD-Associated Triggers in Intestinal Epithelial Cells, Their Correlation to Inflammation and Relevance to IBD Pathogenesis

Carcinoembryogenic antigen cellular adhesion molecules (CEACAMs) are intercellular adhesion molecules highly expressed in intestinal epithelial cells. CEACAM1, -3, -5, -6, -7 are altered in patients suffering from colon cancer and inflammatory bowel diseases (IBD), but their role in the onset and pa...

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Main Authors: Gonzalo Saiz-Gonzalo, Naomi Hanrahan, Valerio Rossini, Raminder Singh, Mary Ahern, Maebh Kelleher, Shane Hill, Ruairi O’Sullivan, Aine Fanning, Patrick T. Walsh, Seamus Hussey, Fergus Shanahan, Ken Nally, Caitriona M. O’Driscoll, Silvia Melgar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.655960/full