Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures

Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures

Pituitary adenylate cyclase activating polypeptide (PACAP) is a neurohormone exerting protective function during various stress conditions either in mature or developing tissues. Previously we proved the presence of PACAP signaling elements in chicken limb bud-derived chondrogenic cells in micromass...

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Bibliographic Details
Main Authors: Tamás Juhász, Eszter Szentléleky, Csilla Szűcs Somogyi, Roland Takács, Nóra Dobrosi, Máté Engler, Andrea Tamás, Dóra Reglődi, Róza Zákány
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
mechanotransduction
chondrocyte differentiation
Sonic hedgehog
Indian hedgehog
hypertrophy
Online Access:http://www.mdpi.com/1422-0067/16/8/17344

Internet

http://www.mdpi.com/1422-0067/16/8/17344

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