Platelet desialylation and TFH cells–the novel pathway of immune thrombocytopenia

Abstract Immune thrombocytopenia (ITP) is an autoimmune disease characterized by immune-mediated destruction of one’s own platelets. The progression of thrombocytopenia involves an imbalance of platelet production and clearance. B cells can induce autoantibodies, and T cells contribute to the pathol...

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Bibliographic Details
Main Authors: Yuwen Chen, Jianda Hu, Yingyu Chen
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Experimental Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s40164-021-00214-5