UGT2B17 genotype and the pharmacokinetic serum profile of Testosterone during substitution therapy with Testosterone Undecanoate. A retrospective experience from 207 men with hypogonadism.

UGT2B17 genotype and the pharmacokinetic serum profile of Testosterone during substitution therapy with Testosterone Undecanoate. A retrospective experience from 207 men with hypogonadism.

BackgroundTestosterone (T) is mainly excreted in the urine as testosterone glucuronide (TG). This glucuronidation is partly dependent on the UGT2B17 genotype, and TG excretion is therefore lower in men having the UGT2B17 deletion. However, the possible influence of UGT2B17 genotype on serum T during...

Full description

Bibliographic Details
Main Authors: Anne Kirstine eBang, Niels eJørgensen, Ewa eRajpert-De Meyts, Anders eJuul
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Endocrinology
Subjects:
Hypogonadism
Testosterone
testosterone treatment
UGT2B17
Testosterone Undecanoate
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00094/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00094/full

Similar Items