Discerning novel splice junctions derived from RNA-seq alignment: a deep learning approach

Abstract Background Exon splicing is a regulated cellular process in the transcription of protein-coding genes. Technological advancements and cost reductions in RNA sequencing have made quantitative and qualitative assessments of the transcriptome both possible and widely available. RNA-seq provide...

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Bibliographic Details
Main Authors: Yi Zhang, Xinan Liu, James MacLeod, Jinze Liu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-018-5350-1