Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice

Abstract Suprachiasmatic nucleus circadian oscillatory protein (SCOP) (a.k.a. PHLPP1) regulates long-term memory consolidation in the brain. Using a mouse model of controlled cortical impact (CCI) we tested if (1) brain tissue levels of SCOP/PHLPP1 increase after a traumatic brain injury (TBI), and...

Full description

Bibliographic Details
Main Authors: Travis C. Jackson, C. Edward Dixon, Keri Janesko-Feldman, Vincent Vagni, Shawn E. Kotermanski, Edwin K. Jackson, Patrick M. Kochanek
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25371-2