Tracing the movement of adiponectin in a parabiosis model of wild-type and adiponectin-knockout mice

Adiponectin is exclusively synthesized by adipocytes and exhibits anti-diabetic, anti-atherosclerotic and anti-inflammatory properties. Hypoadiponectinemia is associated in obese individuals with insulin resistance and atherosclerosis. However, the mechanisms responsible for hypoadiponectinemia rema...

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Bibliographic Details
Main Authors: Hideaki Nakatsuji, Ken Kishida, Ryohei Sekimoto, Tohru Funahashi, Iichiro Shimomura
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:FEBS Open Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211546314000242