Disrupted membrane structure and intracellular Ca²⁺ signaling in adult skeletal muscle with acute knockdown of Bin1.

Disrupted membrane structure and intracellular Ca²⁺ signaling in adult skeletal muscle with acute knockdown of Bin1.

Efficient intracellular Ca²⁺ ([Ca²⁺]i) homeostasis in skeletal muscle requires intact triad junctional complexes comprised of t-tubule invaginations of plasma membrane and terminal cisternae of sarcoplasmic reticulum. Bin1 consists of a specialized BAR domain that is associated with t-tubule develop...

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Bibliographic Details
Main Authors: Andoria Tjondrokoesoemo, Ki Ho Park, Christopher Ferrante, Shinji Komazaki, Sebastian Lesniak, Marco Brotto, Jae-Kyun Ko, Jingsong Zhou, Noah Weisleder, Jianjie Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184157?pdf=render

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http://europepmc.org/articles/PMC3184157?pdf=render

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