IRE1 KNOCKDOWN MODIFIES THE EFFECT OF GLUTAMINE DEPRIVATION ON THE EXPRESSION OF A SUBSET OF PROTEASES IN U87 GLIOMA CELLS

IRE1 KNOCKDOWN MODIFIES THE EFFECT OF GLUTAMINE DEPRIVATION ON THE EXPRESSION OF A SUBSET OF PROTEASES IN U87 GLIOMA CELLS

The aim of this research was to study the effect of glutamine deprivation on the expression of genes encoding for HTRA1/PRSS11, LONP1/PRSS15, and some cathepsins in U87 glioma cells in relation to inhibition of IRE1 (inositol requiring enzyme-1). It was shown that in control glioma cells (transfecte...

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Bibliographic Details
Main Authors: O. V. Halkin, O. O. Riabovol, D. O. Minchenko, A. Y. Kuznetsova, O. O. Ratushna, O. H. Minchenko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2017-08-01
Series:Biotechnologia Acta
Subjects:
RNA expression
HTRA1/PRSS11
LONP1/PRSS15
cathepsins
IRE1 knockdown
glutamine deprivation
Online Access:http://biotechnology.kiev.ua/images/stories/4_2017/halkinminch_4_2017.pdf

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http://biotechnology.kiev.ua/images/stories/4_2017/halkinminch_4_2017.pdf

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