Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011–2013

Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011–2013

Plasmodium falciparum resistance to artemisinin derivatives is emerging in Asia. We examined molecular markers of resistance in 78 children in Uganda who had severe malaria and were treated with intravenous artesunate. We observed in the K13-propeller domain, A578S, a low-frequency (3/78), nonsynony...

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Bibliographic Details
Main Authors: Michael Hawkes, Andrea L. Conroy, Robert O. Opoka, Sophie Namasopo, Kathleen Zhong, W. Conrad Liles, Chandy C. John, Kevin C. Kain
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2015-07-01
Series:Emerging Infectious Diseases
Subjects:
malaria
artesunate
resistance
child
single nucleotide polymorphism
kelch 13 propeller domain
Online Access:https://wwwnc.cdc.gov/eid/article/21/7/15-0213_article

Internet

https://wwwnc.cdc.gov/eid/article/21/7/15-0213_article

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