Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

Similar to other malignancies, urothelial carcinoma (UC) is characterized by specific recurrent chromosomal aberrations and gene mutations. However, the interconnection between specific genomic alterations, and how patterns of chromosomal alterations adhere to different molecular subgroups of UC, is...

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Bibliographic Details
Main Authors: David Lindgren, Gottfrid Sjödahl, Martin Lauss, Johan Staaf, Gunilla Chebil, Kristina Lövgren, Sigurdur Gudjonsson, Fredrik Liedberg, Oliver Patschan, Wiking Månsson, Mårten Fernö, Mattias Höglund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3369837?pdf=render