Cardiorespiratory fitness attenuates age-associated aggregation of white matter hyperintensities in an at-risk cohort

Cardiorespiratory fitness attenuates age-associated aggregation of white matter hyperintensities in an at-risk cohort

Abstract Background Age is the cardinal risk factor for Alzheimer’s disease (AD), and white matter hyperintensities (WMH), which are more prevalent with increasing age, may contribute to AD. Higher cardiorespiratory fitness (CRF) has been shown to be associated with cognitive health and decreased bu...

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Bibliographic Details
Main Authors: Clayton J. Vesperman, Vincent Pozorski, Ryan J. Dougherty, Lena L. Law, Elizabeth Boots, Jennifer M. Oh, Catherine L. Gallagher, Cynthia M. Carlsson, Howard A. Rowley, Yue Ma, Barbara B. Bendlin, Sanjay Asthana, Mark A. Sager, Bruce P. Hermann, Sterling C. Johnson, Dane B. Cook, Ozioma C. Okonkwo
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
White matter hyperintensities
Cardiorespiratory fitness
Online Access:http://link.springer.com/article/10.1186/s13195-018-0429-0

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http://link.springer.com/article/10.1186/s13195-018-0429-0

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