Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro

Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro

The blood-brain barrier (BBB), composed of brain microvascular endothelial cells (BMEC) that are tightly linked by tight junction (TJ) proteins, restricts the movement of molecules between the periphery and the central nervous system. Elevated systemic levels of neutrophils have been detected in pat...

Full description

Bibliographic Details
Main Authors: Anjana Ajikumar, Merete B. Long, Paul R. Heath, Stephen B. Wharton, Paul G. Ince, Victoria C. Ridger, Julie E. Simpson
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
neutrophils
microvesicles
blood brain barrier
endothelial cells
teer
gene expression
permeability
Online Access:https://www.mdpi.com/1422-0067/20/20/5227

Internet

https://www.mdpi.com/1422-0067/20/20/5227

Similar Items