Exacerbated Imiquimod-Induced Psoriasis-Like Skin Inflammation in IRF5-Deficient Mice

Exacerbated Imiquimod-Induced Psoriasis-Like Skin Inflammation in IRF5-Deficient Mice

Interferon regulatory factors (IRFs) play diverse roles in the regulation of the innate and adaptive immune responses in various diseases. In psoriasis, IRF2 is known to be involved in pathogenesis, while studies on other IRFs are limited. In this study, we investigated the role of IRF5 in psoriasis...

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Bibliographic Details
Main Authors: Momoko Nakao, Tomomitsu Miyagaki, Makoto Sugaya, Shinichi Sato
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
interferon regulatory factor 5
psoriasis
imiquimod
IL-23
dendritic cells
interferon regulatory factor 4
Online Access:https://www.mdpi.com/1422-0067/21/10/3681

Internet

https://www.mdpi.com/1422-0067/21/10/3681

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