Potential role of insulin receptor isoforms and IGF receptors in plaque instability of human and experimental atherosclerosis

Potential role of insulin receptor isoforms and IGF receptors in plaque instability of human and experimental atherosclerosis

Abstract Background Clinical complications associated with atherosclerotic plaques arise from luminal obstruction due to plaque growth or destabilization leading to rupture. We previously demonstrated that overexpression of insulin receptor isoform A (IRA) and insulin-like growth factor-I receptor (...

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Bibliographic Details
Main Authors: Nuria Beneit, José Luis Martín-Ventura, Carlota Rubio-Longás, Óscar Escribano, Gema García-Gómez, Silvia Fernández, Giorgio Sesti, Marta Letizia Hribal, Jesús Egido, Almudena Gómez-Hernández, Manuel Benito
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Cardiovascular Diabetology
Subjects:
Atherosclerosis
Insulin receptor isoforms
Insulin-like growth factor receptor
Vascular smooth muscle cells
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12933-018-0675-2

Internet

http://link.springer.com/article/10.1186/s12933-018-0675-2

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