Exposure to Ionizing Radiation Triggers Prolonged Changes in Circular RNA Abundance in the Embryonic Mouse Brain and Primary Neurons

Exposure to Ionizing Radiation Triggers Prolonged Changes in Circular RNA Abundance in the Embryonic Mouse Brain and Primary Neurons

The exposure of mouse embryos in utero and primary cortical neurons to ionizing radiation results in the P53-dependent activation of a subset of genes that is highly induced during brain development and neuronal maturation, a feature that these genes reportedly share with circular RNAs (circRNAs). I...

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Bibliographic Details
Main Authors: André Claude Mbouombouo Mfossa, Helene Thekkekara Puthenparampil, Auchi Inalegwu, Amelie Coolkens, Sarah Baatout, Mohammed A. Benotmane, Danny Huylebroeck, Roel Quintens
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
circular RNA
ionizing radiation
P53 targets
embryonic brain
neuronal maturation
Online Access:https://www.mdpi.com/2073-4409/8/8/778

Internet

https://www.mdpi.com/2073-4409/8/8/778

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