An Adeno-Associated Virus-Based Toolkit for Preferential Targeting and Manipulating Quiescent Neural Stem Cells in the Adult Hippocampus

Summary: Quiescent neural stem cells (qNSCs) with radial morphology are the only proven source of new neurons in the adult mammalian brain. Our understanding of the roles of newly generated neurons depends on the ability to target and manipulate adult qNSCs. Although various strategies have been dev...

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Bibliographic Details
Main Authors: Andrew J. Crowther, Szu-Aun Lim, Brent Asrican, Blake H. Albright, Josh Wooten, Chia-Yu Yeh, Hechen Bao, Domenic H. Cerri, Jessica Hu, Yen-Yu Ian Shih, Aravind Asokan, Juan Song
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118300444