Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants

Maintaining protein integrity at the inner nuclear membrane (INM) is critical for eukaryotic cellular function. Here, using proximity-labeling proteomics, Huang et al. profile the INM in Arabidopsis and identify the CDC48 complex and PUX proteins as components of an INM protein degradation pathway.

Bibliographic Details
Main Authors: Aobo Huang, Yu Tang, Xuetao Shi, Min Jia, Jinheng Zhu, Xiaohan Yan, Huiqin Chen, Yangnan Gu
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16744-1