LOXL1 Is Regulated by Integrin α11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity

LOXL1 Is Regulated by Integrin α11 and Promotes Non-Small Cell Lung Cancer Tumorigenicity

Integrin α11, a stromal collagen receptor, promotes tumor growth and metastasis of non-small cell lung cancer (NSCLC) and is associated with the regulation of collagen stiffness in the tumor stroma. We have previously reported that lysyl oxidase like-1 (LOXL1), a matrix cross-linking enzyme...

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Bibliographic Details
Main Authors: Cédric Zeltz, Elena Pasko, Thomas R. Cox, Roya Navab, Ming-Sound Tsao
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
lysyl oxidase
integrin α11
lung adenocarcinoma
matrix cross-linking
tumor progression
Online Access:https://www.mdpi.com/2072-6694/11/5/705

Internet

https://www.mdpi.com/2072-6694/11/5/705

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