Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes

Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes

Genes can encode multiple isoforms, broadening their functions and providing a molecular substrate to evolve phenotypic diversity. Evolution of isoform function is a potential route to adapt to new environments. Here we show that de novo, beneficial alleles in the nurf-1 gene became fixed in two lab...

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Bibliographic Details
Main Authors: Wen Xu, Lijiang Long, Yuehui Zhao, Lewis Stevens, Irene Felipe, Javier Munoz, Ronald E Ellis, Patrick T McGrath
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
other Caenorhabditis species
Isoform evolution
adaptive conflict
alternative transcripts
chromatin remodeling
Online Access:https://elifesciences.org/articles/48119

Internet

https://elifesciences.org/articles/48119

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