Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata

Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata

In our search for new antiplasmodial agents, the CH2Cl2/CH3OH (1:1) extract of the roots of Tephrosia aequilata was investigated, and observed to cause 100% mortality of the chloroquine-sensitive (3D7) strain of Plasmodium falciparum at a 10 mg/mL concentration. From this extract three new chalconoi...

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Bibliographic Details
Main Authors: Yoseph Atilaw, Sandra Duffy, Matthias Heydenreich, Lois Muiva-Mutisya, Vicky M. Avery, Máté Erdélyi, Abiy Yenesew
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
Tephrosia aequilata
chalcone
retrochalcone
aequichalcone A
aequichalcone B
aequichalcone C
pterocarpene
antiplasmodial
Online Access:http://www.mdpi.com/1420-3049/22/2/318

Internet

http://www.mdpi.com/1420-3049/22/2/318

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