An in vitro model to explore subchondral perfusion and intraosseous pressure

An in vitro model to explore subchondral perfusion and intraosseous pressure

Abstract Background Little is known about subchondral perfusion physiology. We developed a 3Rs (Replace, Reduce, Refine) compliant in vitro calf foot model to explore perfusion and intraosseous pressure (IOP). Methods Calf feet were catheterised and perfused with serum. IOP was measured at three sit...

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Bibliographic Details
Main Authors: Michael Beverly, David Murray
Format: Article
Language:English
Published: SpringerOpen 2019-08-01
Series:Journal of Experimental Orthopaedics
Subjects:
Intraosseous pressure
Perfusion
Physiology
Subchondral
In vitro model
Tourniquet
Online Access:http://link.springer.com/article/10.1186/s40634-019-0207-3

Internet

http://link.springer.com/article/10.1186/s40634-019-0207-3

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