Phosphorylation at S153 as a Functional Switch of Phosphatidylethanolamine Binding Protein 1 in Cerebral Ischemia-Reperfusion Injury in Rats

Phosphorylation at S153 as a Functional Switch of Phosphatidylethanolamine Binding Protein 1 in Cerebral Ischemia-Reperfusion Injury in Rats

This study aimed to estimate the role of phosphatidylethanolamine binding protein 1 (PEBP1) in cerebral ischemia-reperfusion (I/R) injury and the underlying mechanisms. Middle cerebral artery occlusion/reperfusion (MCAO/R) model in adult male Sprague Dawley rats (250–280 g) were established and cult...

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Bibliographic Details
Main Authors: Zhong Wang, Jiyuan Bu, Xiyang Yao, Chenglin Liu, Haitao Shen, Xiang Li, Haiying Li, Gang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
cerebral ischemia-reperfusion injury
phosphatidylethanolamine binding protein 1
phosphorylation
apoptosis
inflammation
rats
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00358/full

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http://journal.frontiersin.org/article/10.3389/fnmol.2017.00358/full

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