Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide

Reduction and Preparation of a Phthalimide Derivative from a Furo-heliangolide

Goyazensolide, a biologically active natural product classified as a furoheliangolide, was transformed in a phthalimide derivative that showed an enhanced biological activity against Tripanosoma cruzi. The complex natural product was also reduced with high stereoselectivity by hydrogen/Wilkinsonâ€...

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Bibliographic Details
Main Authors: Mauricio Gomes Constantino, Vladimir Constantino Gomes Heleno, Gil Valdo José da Silva
Format: Article
Language:English
Published: MDPI AG 2000-06-01
Series:Molecules
Subjects:
Furo-heliangolides
Goyazensolide
Reduction
Phthalimide derivative
Wilkinson’s catalyst
Online Access:http://www.mdpi.com/1420-3049/5/6/908/

Internet

http://www.mdpi.com/1420-3049/5/6/908/

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