Characterization of the Pharmacokinetics of Samidorphan in Healthy Volunteers: Absolute Bioavailability and the Effect of Food and Age
Abstract Background and Objectives Samidorphan (SAM) is a novel μ-opioid receptor antagonist. We report clinical pharmacokinetic (PK) properties of SAM following different routes of administration, and the effects of food and age on the PK of SAM following oral administration in healthy volunteers....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Adis, Springer Healthcare
2019-08-01
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| Series: | Drugs in R&D |
| Online Access: | http://link.springer.com/article/10.1007/s40268-019-00280-5 |