Putative hexameric glycosyltransferase functional unit revealed by the crystal structure of Acinetobacter baumannii MurG

Putative hexameric glycosyltransferase functional unit revealed by the crystal structure of Acinetobacter baumannii MurG

Lipid II, the main component of the bacterial cell wall, is synthesized by the addition of UDP-N-acetylglucosamine to the UDP-N-acetylmuramic acid pentapeptide catalyzed by the glycosyltransferase MurG. Owing to its critical role in cell-wall biosynthesis, MurG is considered to be an attractive targ...

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Bibliographic Details
Main Authors: Kyoung Ho Jung, Sunghark Kwon, Chang Min Kim, Jun Hyuck Lee, Hyun Ho Park
Format: Article
Language:English
Published: International Union of Crystallography 2021-07-01
Series:IUCrJ
Subjects:
acinetobacter baumannii
cell-wall peptidoglycan biosynthesis
crystal structure
glycosyltransferases
murg
superbugs
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252521003729

Internet

http://scripts.iucr.org/cgi-bin/paper?S2052252521003729

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