A mid-life vitamin A supplementation prevents age-related spatial memory deficits and hippocampal neurogenesis alterations through CRABP-I.

A mid-life vitamin A supplementation prevents age-related spatial memory deficits and hippocampal neurogenesis alterations through CRABP-I.

Age-related memory decline including spatial reference memory is considered to begin at middle-age and coincides with reduced adult hippocampal neurogenesis. Moreover, a dysfunction of vitamin A hippocampal signalling pathway has been involved in the appearance of age-related memory deficits but als...

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Bibliographic Details
Main Authors: Katia Touyarot, Damien Bonhomme, Pascale Roux, Serge Alfos, Pauline Lafenêtre, Emmanuel Richard, Paul Higueret, Véronique Pallet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3747058?pdf=render

Internet

http://europepmc.org/articles/PMC3747058?pdf=render

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