A Genetic Cascade of let-7-ncl-1-fib-1 Modulates Nucleolar Size and rRNA Pool in Caenorhabditis elegans.

A Genetic Cascade of let-7-ncl-1-fib-1 Modulates Nucleolar Size and rRNA Pool in Caenorhabditis elegans.

Ribosome biogenesis takes place in the nucleolus, the size of which is often coordinated with cell growth and development. However, how metazoans control nucleolar size remains largely unknown. Caenorhabditis elegans provides a good model to address this question owing to distinct tissue distributio...

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Bibliographic Details
Main Authors: Yung-Hsiang Yi, Tian-Hsiang Ma, Li-Wei Lee, Pey-Tsyr Chiou, Po-Hsiang Chen, Ching-Ming Lee, Yu-De Chu, Hsiang Yu, Kuei-Ching Hsiung, Yi-Tzang Tsai, Chi-Chang Lee, Yu-Sun Chang, Shih-Peng Chan, Bertrand Chin-Ming Tan, Szecheng J Lo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4619655?pdf=render

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http://europepmc.org/articles/PMC4619655?pdf=render

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