Mutagenic Study of Benzimidazole Derivatives with (+S9) and without (−S9) Metabolic Activation

Mutagenic Study of Benzimidazole Derivatives with (+S9) and without (−S9) Metabolic Activation

Benzimidazole derivatives have a diverse range of biological activities, including antiulcer, antihypertensive, antiviral, antifungal, anti-inflammatory, and anticancer. Despite these activities, previous studies have revealed that some of the derivatives can induce mutations. This study aimed to sc...

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Bibliographic Details
Main Authors: Nurul Hafizan Azahar, Siti Soleha Ab dullah, Rozaini Abdullah, Norizan Ahmat, Abdah Md Akim, Hasiah Ab Hamid
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
benzimidazole
Ames test
structure–activity relationship (SAR)
Online Access:https://www.mdpi.com/1422-0067/20/18/4324

Internet

https://www.mdpi.com/1422-0067/20/18/4324

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