Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.

Coronaviruses recognize a variety of receptors using different domains of their envelope-anchored spike protein. How these diverse receptor recognition patterns affect viral entry is unknown. Mouse hepatitis coronavirus (MHV) is the only known coronavirus that uses the N-terminal domain (NTD) of its...

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Bibliographic Details
Main Authors: Jian Shang, Yushun Wan, Chang Liu, Boyd Yount, Kendra Gully, Yang Yang, Ashley Auerbach, Guiqing Peng, Ralph Baric, Fang Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008392