The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells

<p>Abstract</p> <p>Background</p> <p>Many cancer cells develop resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis, necessitating combination with chemotherapy, and normal cells manifest side effects due to the combined treatm...

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Bibliographic Details
Main Authors: Li Jianyong, Qin Yong, Tang Hongyun, Gong Xingguo
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/18