Genetic Dissection of a QTL Affecting Bone Geometry

Genetic Dissection of a QTL Affecting Bone Geometry

Parameters of bone geometry such as width, length, and cross-sectional area are major determinants of bone strength. Although these traits are highly heritable, few genes influencing bone geometry have been identified. Here, we dissect a major quantitative trait locus (QTL) influencing femur size. T...

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Bibliographic Details
Main Authors: Olivia L. Sabik, Juan F. Medrano, Charles R. Farber
Format: Article
Language:English
Published: Oxford University Press 2017-03-01
Series:G3: Genes, Genomes, Genetics
Subjects:
quantitative trait loci (QTL)
bone geometry
bone strength
QTL fine-mapping
allele-specific expression (ASE)
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.037424

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.037424

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