Definition of a New Metric With Mutual Exclusivity and Coverage for Identifying Cancer Driver Modules

Definition of a New Metric With Mutual Exclusivity and Coverage for Identifying Cancer Driver Modules

Identification of cancer driver modules or pathways is a key step in understanding cancer pathogenesis and exploring patient-specific treatments. Numerous studies have shown that some genes with low mutation frequency are also important for the cancer progression, while previous research have focuse...

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Bibliographic Details
Main Authors: Wei Zhang, Yue Liu, Wang Lei Wang Lei
Format: Article
Language:English
Published: IEEE 2020-01-01
Series:IEEE Access
Subjects:
Driver modules
mutual exclusivity
mutation impact distance
low-frequency mutation
ant colony optimization algorithm
Online Access:https://ieeexplore.ieee.org/document/9146111/

Internet

https://ieeexplore.ieee.org/document/9146111/

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