A Novel Protein Interaction between Nucleotide Binding Domain of Hsp70 and p53 Motif

Currently, protein interaction of Homo sapiens nucleotide binding domain (NBD) of heat shock 70 kDa protein (PDB: 1HJO) with p53 motif remains to be elucidated. The NBD-p53 motif complex enhances the p53 stabilization, thereby increasing the tumor suppression activity in cancer treatment. Therefore,...

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Bibliographic Details
Main Authors: Asita Elengoe, Mohammed Abu Naser, Salehhuddin Hamdan
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2015/391293