A Novel Protein Interaction between Nucleotide Binding Domain of Hsp70 and p53 Motif
Currently, protein interaction of Homo sapiens nucleotide binding domain (NBD) of heat shock 70 kDa protein (PDB: 1HJO) with p53 motif remains to be elucidated. The NBD-p53 motif complex enhances the p53 stabilization, thereby increasing the tumor suppression activity in cancer treatment. Therefore,...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
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Series: | International Journal of Genomics |
Online Access: | http://dx.doi.org/10.1155/2015/391293 |