Genetic Restrictive Cardiomyopathy: Causes and Consequences—An Integrative Approach

Genetic Restrictive Cardiomyopathy: Causes and Consequences—An Integrative Approach

The sarcomere as the smallest contractile unit is prone to alterations in its functional, structural and associated proteins. Sarcomeric dysfunction leads to heart failure or cardiomyopathies like hypertrophic (HCM) or restrictive cardiomyopathy (RCM) etc. Genetic based RCM, a very rare but severe d...

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Bibliographic Details
Main Authors: Diana Cimiotti, Heidi Budde, Roua Hassoun, Kornelia Jaquet
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
cardiomyopathy
restrictive cardiomyopathy
pediatric
sarcomere
contractile dysfunction
calcium
Online Access:https://www.mdpi.com/1422-0067/22/2/558

Internet

https://www.mdpi.com/1422-0067/22/2/558

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