Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair.

Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repair.

Jaagsiekte sheep retrovirus (JSRV) is a unique oncogenic virus with distinctive biological properties. JSRV is the only virus causing a naturally occurring lung cancer (ovine pulmonary adenocarcinoma, OPA) and possessing a major structural protein that functions as a dominant oncoprotein. Lung cance...

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Bibliographic Details
Main Authors: Claudio Murgia, Marco Caporale, Ousman Ceesay, Gabriella Di Francesco, Nicola Ferri, Vincenzo Varasano, Marcelo de las Heras, Massimo Palmarini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3068994?pdf=render

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http://europepmc.org/articles/PMC3068994?pdf=render

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